ISMRC 2023 Final Programme

16 Scientific Programme – Wednesday, 3 May 2023 SESSION 4 Liquid Biopsy and Immuno-Oncology Chairs: Christoffer Gebhardt, Germany Paul Hofman, France 09:00 – 09:30 a.m. Targeting mismatch repair with immu- notherapy Luis Diaz, USA 09:30 – 10:00 a.m. The power of circulating tumor cells in Immuno-Oncology Catherine Alix-Panabières, France 10:00 – 10:15 a.m. Circulating cell-free DNA and circula- ting tumor cells as prognostic biomar- kers in stage III melanoma Anthony Lucci, USA 10:15 – 10:30 a.m. Circulating tumor DNA (ctDNA) as sen- sitive and specific biomarker in stage I to III malignant melanoma Eva Dazert-Klebsattel, Germany 10:30 – 11:00 a.m. Coffee Break SESSION 5 Immunotherapy for Prevention of Metastatic Progression – Part I Chairs: Katja Weisel, Germany Laurence Zitvogel, France 11:00 – 11:30 a.m. Harnessing Natural Killer cells in cancer Eric Vivier, France 11:30 a.m. – 12:00 p.m. Claudin6-directed therapy approaches in solid tumors Carsten Bokemeyer, Germany 12:00 – 12:15 p.m. Targeting the AKT/mTOR pathway at- tenuates the metastatic potential of colorectal carcinoma CTCs in a murine xenotransplantation model and alters metabolic pathways Daniel J. Smit, Germany 12:15 – 12:30 p.m. Circulating tumor cell enumeration and ultradeep T-cell receptor-sequencing in a Phase I clinical trial of metastatic pro- state cancer Karl-Henning Kalland, Norway 12:30 – 02:00 p.m. Lunch Break