259 / 366
Objective:
The aim of this study was to determine the utility of cell
blocks (CB) in the diagnosis of thyroid cytology.
Method:
Over a period of 3 months, 468 cases underwent ultra-
sound guided thyroid fine needle aspiration, conventional cytolo-
gy, liquid-based cytology (LBC) and CB evaluation. CBs were
prepared from the residual aspirate LBC boxes. The contribution
of the CB findings to the final diagnosis was assessed.
Results:
Conventional cytology and LBC results were as follows:
Bethesda I, %14.4 (
n
= 81); Bethesda II, %74,2 (
n
= 416); Bethesda III,
%4,6 (
n
= 26); Bethesda IV, %1,2 (
n
= 7); Bethesda V,% 2.5 (
n
= 14), and
Bethesda VI, %2,8 (
n
= 16). After combined cytological and CB evalu-
ation, overall 60 cases (%10,7) final diagnosis has changed regardless of
Bethesda category.Initially cytological diagnosis was non-diagnostic
(Bethesda I) in 81 cases. CB changed the impression in 43 cases (%53)
and this change was statistically significant (
p
< 0.001).Initially cytolog-
ical diagnosis was AUS/FLUS (Bethesda III) in 26 cases. After addition
of CB findings, 6 cases diagnosis has changed (
p
< 0.001).
Conclusion:
The contribution of the CB in the diagnosis of thy-
roid lesions are striking. Specifically, the samples that benefited
most were initially non-diagnostic specimens and selected cases of
AUS/FLUS while benign samples gained little additional
information.
PS-20-001
Impact of Leningrad/Petersburg school upon pathology of respirato-
ry infections
V. Zinserling
*
*
Institute Experimental Medicine, Dept. of Pathology, St. Petersburg,
Russia
Objective:
Respiratory viral and bacterial infections still play an impor-
tant role in morbidity and mortality all over the world, but in the literature
the peculiarities of lesions due to single pathogen are very scare. The
results of studies provided by V.D. Zinserling (1891
–
1960) and A.V.
Zinserling (1923
–
1995) in Saint-Petersburg, Russia are not well known
in world literature due to objective reasons.
Method:
Analyze the results of long term studies of their scientific school
and reveal the original concepts still being of high value.
Results:
Main statements in the V.D. Zinserling
’
s doctrine of pneumonias
(primarily formulated in 1939): in typical cases there is distinct correlation
between etiology and pathological pattern of pneumonias; pneumonias due
to pneumococci, staphylococci, streptococci, haemophilus have their pecu-
liarities; croupose pneumonia is always caused by pneumococci, the so
called stages in hepatization according to Carl Rokitanski are only variants
of the disease. A. Zinserling described as the first (or partly seriously spec-
ified) the microscopical changes in influenza, parainfluenza, respiratory-syn-
cytial, mycoplasma and chlamydial infections allowing preliminary evalua-
tion of etiology; developed the concept of clinical importance of mixed
infections in lesions of lungs and other organs.
Conclusion:
The result obtained by Zinserling
’
s scientific school has to
be taken in consideration nowadays.
PS-20-002
Learning to observe. Observing to learn. The antique dermatological
waxes of the Pathology Museum of the University of Florence
R. Santi
*
, G. Nesi
*
University of Florence, Pathological Anatomy Section, Italy
Objective:
IIn the past centuries, the making of wax moulages was an
exclusive and sought-after art that was primarily used for teaching anatomy
and pathology. Dermatology has benefitted from wax duplicates, which are
not only tri-dimensional but also offer the
“
dimension
”
of colour, an essential
element for a correct gross diagnosis. The Pathology Museum, part of the
Museum of Natural History of the University of Florence, houses anatomical
specimens and more than a hundred waxes of astounding beauty, almost
photographic reproductions of the most common diseases in the nineteenth
century, when the collection was set up.
Method:
The original Catalogue of the museum was perused for
moulages depicting skin diseases, together with their relevant clin-
ical and/or autopsy findings.
Results:
The wax collection of the Pathology Museum includes 29 der-
matological models such as papulo-squamous disorders as well as infec-
tious and neoplastic diseases.
Conclusion:
The collection of skin moulages of the University of
Florence constitutes a precious historical heritage of high scientif-
ic and artistic value. Silently but loudly, these models also intro-
duce visitors to the dramatic psycho-social consequences of
defacing diseases, still a difficult task for the contemporary phy-
sician.
PS-20-003
On moral and political philosophy of pathology in context of UNO-
Agenda 21
E. Neu
*
, M. C. Michailov, U. Welscher, G. Ernst, T. Senn, C. Lütge, I.
Ivanova, M.-L. Gräfin von Brockdorff, A. Hofstetter, E. R. Weissenbacher,
J. Foltinova, V. Foltin, M. Schratz, G. Weber
*
Inst. Umweltmed. c/o ICSD e.V., München, Germany
Objective:
Pathology is a-priori central biomedical-discipline with
moral&scientific responsibility counteracting disastrous health-situation
of humanity&ecological-destruction.
Method:
see Ref. IAP-2016 Köln Eur.J.Pathol. 469:S1 PS-20-007.
Philosophy: IUPsyS-2008-Berlin IntJPsychol 43:154/248/615/799.
Results:
CONCEPTION: Pathology is to be discussed in context of hu-
manization/higher-effectiveness, interdisciplinarity. a. Foundation of de-
partments for philosophical-pathology and integration in
education&research. b. Foundation of national-continental-international
pathol.-institutes via network of selected countries related to
international-universities by G.MENSCHING & B.RUSSELL/Nobel-
Laureate. c. Implication of pathological topics to intern. congresses for
philosophy-FISP/psychology-IUPsyS/physiology-IUPS/biophysics-
IUPAB/chemistry-IUPAC, also clinical-medicine: IUPHAR/FIGO/ISIM/
ISR/SIU/etc. d. Enlargement of International Academy for Pathology/
IAP by (sub-)continental/African-American-Australo-Asian/Chinese-
Indian-European-national branches of IAP, independently from patholog-
ical-societies. Fundamentals for a-d conc. pathology: 1. International ed-
u c a t i o n a l / r e s e a r c h - p r o g r a m m e s . 2 . C o m m o n
administration&laboratories. 3. Recognition of participants as intern./
continental professors/doctors-etc./EU-UNO-employees? 4. Possibility
for work in IAP-institutes/branches. 5. Regular successive financial-
support for participants/projects by nat.-ministries/industry/Eur.-Union/
UNESCO-etc. 6. Possibility for whole-life-work after 60 years as
senior-scientists incl. honorary-professors&institut-directors-etc.
Conclusion:
Implication of a-d&1-6 in pathology will help UNO-Agenda21
for better health&education in all countries. Support of IAP conc. proposals
by governments-foundations-EU-UNESCO-WHO is necessary.
PS-20-004
The questionnaire portraits of five Russian pathologists
A. Zubritsky
*
*
Moscow, Russia
Wednesday, 6 September 2017, 09:30
–
10:30, Hall 3
PS-20 History of Pathology
Virchows Arch
(
2017
)
471
(
Suppl 1
):
S1
–
S352
S245