ECP 2017 - Abstract Book

Objective:

In cases presented with lymphadenopathies without a primary

focus found by simple radiological methods, the primary tumour can be

diagnosed by histopathological evaluation of the metastatic lymph nodes.

We aimed to discuss the nonhematological malignancies presented with

lymphadenopathies and the histopathological results for primary tumours.

Method:

In this retrospective study, cases diagnosed with metastasis in ex-

cisional lymph nodes between January 2013 and June 2016 were assessed for

histopathological diagnostic approach and their relation with further clinical

results.

Results:

Among 832 lymph node biopsies, a total number of 21 cases, 12

male and 9 female, with a mean age of 57,23 (33

–

92) presented with

nonhematological solid tumours were included. The most common localiza-

tions of the involved lymph nodes were inguinal (

= 8), axillary (

= 6),

cervical (

= 4), and supraclavicular (

= 3) region. The most common

primary tumours were malignant melanoma (

= 6), breast carcinoma

(

= 4), ovarian carcinoma (

= 2), squamous cell carcinoma (

= 2), and

germ cell tumour (

= 2). Others were papillary thyroid carcinoma, renal cell

carcinoma, urothelial carcinoma, prostate adenocarcinoma and endometrial

adenocarcinoma.

Conclusion:

Nonhematological malignancies presented with lymphadenop-

athies are one of the most complicated occasions for clinicians. The histo-

pathological evaluation of the excisional metastatic lymph node biopsies is an

important method because of the cost effectiveness and easy applicability.

E-PS-14-003

Analysis, human resources reorganisation and quality management

system implementation in an Anatomic Pathology Department

C. B. Marta*, T. Ramirez, B. Maria, A. B. Lafuente, M. Chico, L. Floria

*HCU Lozano Blesa, Anatomia Patologica, Zaragoza, Spain

Objective:

Our Pathology department is composed by highly qualified

personnel, distributed by areas of clinical and technical training, with

some deficiencies in response times.

Method:

The analysis of the current situation has been carried out, in-

cluding strengths and weaknesses, always focused on optimization and

deficiencies correction. In order to achieve this, indicators of productivity,

labour safety standards, continuous training, and adequacy of personnel

have been used. During 12 months, the redistribution of resources by

areas of training, and the existing delays are analyzed. Training work-

shops are held, equipment is relocated and new modern communication

channels are established.

Results:

A Quality Commission group was reactivated involving

phisician and lab technicians, interacting with the Hospital Main

Quality Commission, in order to apply European regulations, Spanish

society of pathology and prevention of occupational hazards

recommendations.

Conclusion:

We have achieved improvements in the staff qualification,

participation of all personal in any service decision and basic training that

favours completion of the tasks. Actually, there is still a shortage of pathol-

ogists and technical personal, although the involvement of all members

admits raising expectations to achieve objectives. Our goal in the future is

start up department accreditation towards norm UNE-EN ISO 15189.

E-PS-15-001

Bronchogenic cyst with an extremely rare lipoma-like appearance:

Case report

A.-S. Varban*, E. Magheran, S. Vlasceanu, I. Cordos

*Bucharest Emergency University, Dept. of Pathology, Romania

Objective:

Bronchogenic cysts are congenital malformations, usually

asymptomatic, resulting by abnormal development of the ventral foregut

and lung budding during the first trimester. We present an extremely rare

case of a lipoma-like bronchogenic cyst.

Method:

A 38 years-old old man came in the Pneumology Department of

Marius Nasta Hospital with irritative cough. Imagistic explorations re-

vealed an anterior-superior mediastinal tumour. The surgeon removed a

well demarcated mass that was molding the vasculare structures, without

invasion. The tumour was sent to Pathology Department for further pro-

cedures and histopathological examination.

Results:

The tumour ( 11/11,5/7 cm) had smooth external surface

and a thin, transparent capsule. Cut surface was polymorph with

fatty areas intricated with multiple cysts (yellowish-green

gelatinous content) and pearlescent, glossy zones. The thickness

of the cysts walls was 1

–

3 mm, with focal calcifications.

Microscopy revealed matur adipous tissue, cystic areas, fibro-

colagenotic tissue and calcifications. The inner surface of the

cysts was lined by respiratory-type epithelium (pseudostratified

columnar, ciliated) with submucosal glands, fascicles of smooth

muscle and mature cartilage.

Conclusion:

This bronchogenic cyst has an extremely rare lipoma-like

appearance. We found only one similar case published in speciality liter-

ature. Other particularities are: multiple cysts, calcification ( 10 % of

cases) and symptomatic presentation.

E-PS-15-002

Malignant pleural mesothelioma with no asbestos history: A case

report

A. S. Postolache*, I. Dumitru, S. A. Varban, A. Tudor, D. Leonte

*Emergency University Hospital, Dept. of Pathology, Bucharest,

Romania

Objective:

Malignant pleural mesothelioma (MPM) is a rare and

highly aggressive tumour arising from the mesothelial surface of

the pleural space.This tumour was once rare, but its incidence

rates are predicted to peak in the next few years.

Method:

MPM is difficult to treat and commonly associated with asbes-

tos exposure, which is its main risk factor.

Results:

This cancer is a challenging diagnosis to make because of the

insidious onset of symptomatology that leads to advanced stage and poor

prognosis. The median survival rate is around 12 months. We present a

case of a 59 year-old patient with no asbestos exposure who presented

with left pleural hemorrhagic effusion and pleural thickening on CT scan.

Conclusion:

Our pathology department confirmed the bleak diagnosis of

diffuse epithelioid malignant mesothelioma, with pericardial and dia-

phragmatic invasion and lymph node metastasis.

E-PS-15-004

Combined small cell carcinoma: A report of a case and a potential

pitfall

I. Provatas*, N. Baltayannis, G. Vecchini, H. Trihia

*Evangelismos General Hospital, Dept. of Pathology, Athens, Greece

Objective:

Combined small cell lung carcinomas (CSCLCs) are small

cell lung carcinomas (SCLCs) containing areas of non

–

small cell compo-

nents (NSCLC), such as adenocarcinoma, squamous cell carcinoma, and

large cell neuroendocrine carcinoma (LCNEC). We present a case of a

patient diagnosed with a NSCLC on frozen sections and CSCLC on the

resection specimen.

Method:

A 63-year-old patient was referred to our hospital with a mass

lesion of his right lower lobe and a tumour nodule of the upper right lobe.

Intraoperatively, frozen sections were diagnostic of a NSCLC. He

underwent a right low lobectomy and an upper lobe tumour resection.

E-PS-15 Pulmonary Pathology

Virchows Arch

(

2017

)

471

(

Suppl 1

–

S352

S338