ECP 2017 - Abstract Book

secondary to a disseminated lymphoma. A primary breast lymphoma

diagnosis should be given after excluding secondary involvement.

Almost all of the primary breast lymphomas are Non-Hodgkin

Lymphoma. Diffuse large B cell lymphoma is the most common subtype.

Method:

A 23 year-old female patient presented with a breast mass of

2 months duration. Patient

’

s physical and radiological examination didn

’

reveal any lymphadenopathy. Hematologic examination results were

within normal limits.

Results:

Aspirate from the mass included clusters of atypical lymphoid

cells exhibiting narrow cytoplasm,large nuclei and small nucleoli with

numerous mitotic figures. On immunochemistry study of cell block, these

cells showed positivity for LCA, CD 20 , BCL2 and negativity for CK 7.

We diagnosed the patient as

“

Non-Hodgkin lymphoma, B cell type

”

Conclusion:

Cytological diagnosis of primary breast lymphoma has sig-

nificance as the management of the patient change.

E-PS-04-015

Pancreatic mx diagnosis of Clear Renal Cell Carcinoma (CRCC) by

fnab- eus-guided: Review of 2 cases

V. Caamaño Villaverde

, M. Gonzalez Vadillo, L. Mosteiro Gonzalez, M.

Saiz Camín, V. Velasco Benito, L. Andres Alvarez, A. Nogueira

Gregorio, G. García de Casasola, S. Malaxetxebarria Unibaso, L.

Zaldumbide Dueñas

Hospital Universitario Cruces, Dept. of Pathology, Barakaldo, Spain

Objective:

The pancreatic MX of CRCC is little frequent (1

–

2.8 %),

since it usually occurs as single pancreatic nodule, with an interval be-

tween the resection of the primary tumour and the MX that can be very

long (up to 30 years). Conservative surgical resection is the treatment of

choice.

Method:

Case 1: 82-year-old male diagnosed in April 2016 from CRCC

(grade IV of Fuhrman) pT3a. Case 2: 55-year-old woman diagnosed in

1999 by CRCC invading adipose tissue and venous vessels hilar with

lymph node relapse in 2000.

Results:

Endoscopic Ultrasound (EUS)-EUs-guided Fna, obtaining ma-

terial for extended cytologic and citobloque which are techniques of SWI.

In both cases obtained atypical cells are positive for CD-10; Vimentin and

Renal CC, which confirms the Presurgical diagnosis of Metastasis of

renal clear Cell Carcinoma.

Conclusion:

Before a solid, well defined patient diagnosed of CRCC

injury should be suspected MX although the disease-free period is very

long. The realization of citobloque with the material obtained by Fna

(EUS) is high-value diagnostic. Techniques of SWI for the preoperative

diagnosis of the lesion and select patients with CRCC MX for the con-

servative surgical resection, it improves survival and quality of life of the

patient.

E-PS-05-001

A diagnostic challenge in the conundrum of basal cell carcinoma with

trichoblastic-like differentiation versus trichoblastic carcinosarcoma

E. Olteanu

, I. M. Mihai, D. Szilagyi, A. Dema

SCJUT Pius Brinzeu, Dept. of Pathology, Timisoara, Romania

Objective:

The case of a 58-year-old male patient presenting with a right

preauricular mass and the difficulty the histopathological aspects of this

type of case represents

Method:

Grossing of the tissue with histological slides preparation using

hematoxylin and eosin and immunohistochemical stains

Results:

Histological sections revealed a poorly circumscribed, infiltra-

tive neoplasm composed of epithelial cells arranged in lobules with pe-

ripheral palisading and focal retraction of the stroma, numerous and focal

keratotic areas with adnexal differentiation. The proliferating mass

showed vascular and nerve tropism. Immunohistochemically the epithe-

lial component of the tumour was weakly to moderately positive for Ber-

EP4, moderately to intensely positive for AE1/AE3 and negative for

Vimentin and EMA, while the sarcomatoid component was negative for

Ber-EP4 and AE1/AE3, and positive for Vimentin. At the periphery of the

proliferating mass, there were aspects that resembled follicular stroma

with CK20 focal positivity.

Conclusion:

Consulting the literature and weigh in the histological and

immunohistochemical findings a diagnosis of trichoblastic carcinosarco-

ma is proposed

E-PS-05-002

Analysis of nasal skin biopsies: A 354-case series

A. Kilitci

, Y. Cicek, E. Acer

Ahi Evran University Hospital, Dept. of Pathology, Kirsehir, Turkey

Objective:

The aim of this study was to review the main lesion

types of the nasal skin and to present a comprehensive list of the

diseases that affect the skin that can involve the nose.Incisional/

excisional biopsy with histopathological study is a must in all

types of small masses in nose.

Method:

A study of 354 patients was done,specimen collected and sub-

jected to histopathological study.These masses were further classified as

nonneoplastic (inflammatory, cysts..),benign,premalignant and malignant

lesions and the frequency of their occurrence in K

rsehir region,their age

and sex distribution were observed.

Results:

In general,benign neoplasms were the most common in all

l e s i o n s ( 6 5 . 2 % ,

= 2 3 1 ) f o l l o w e d b y m a l i g n a n t

neoplasms(20.1 %,

= 71),non neoplastic lesions(9.6 %,

= 34) and pre-

malignant neoplasms (5.1 %,

= 18).Nevus(175),basal cell carcino-

ma(67) and chronic non-specific inflammations(21) were commonest

lesions.In malignant neoplasms basal cell carcinoma(67) was more com-

m o n t h a n s q u a m o u s c e l l c a r c i n o m a ( 4 ) ; i n b e n i g n

neoplasms,nevus(175),vascular tumours(13) and verruca vulgaris(11)

were mostly diagnosed.In premalignant lesions,actinic keratosis(11) and

keratoacanthoma(7) were found in 18 patients.Females(226) were more

affected than males(128).There were 20 cases under 18 year

old.Adolescents/children didn

’

t affected for premalignant and malignant

neoplasms.

Conclusion:

Any disease that affects the face and nose,mostly depends

on ultraviolet exposure.As a result of heterogeneity of skin lesions of the

nose,proper education of clinicians and excision biopsy with histopatho-

logical study are compulsory.

E-PS-05-003

Gigantic extraocular sebaceous carcinoma: A case report

A. Ciobanu

, M. Costache

Emergency University Hospital, Pathology, Bucharest, Romania

Objective:

Sebaceous carcinomas are malignant adnexal skin tumours

expressing sebocytic differentiation. According to the site of involve-

ment, these neoplasms are classified as ocular or extraocular, with no

biological differences, ocular location being more frequent.

Method:

We report a case of a 66-year-old woman with a history of

breast carcinoma, NST, presenting with a gigantic, exophytic, ulcerated,

epicranial tumour mass, measuring 110/74/40 mm.

Results:

On gross examination, the tumour appeared sessile, whitish,

having an irregular, ulcerated surface, with a hematic crust. The cut sec-

tion revealed areas of hemorrhage and necrosis. The mass was totally

E-PS-05 Dermatopathology

Virchows Arch

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2017

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471

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